L.M. Veenendaal, R. van Hillegersberg, N. Smakman, J.D.W. van der Bilt, P.J. van Diest, O. Kranenburg, I.H.M. Borel Rinkes; Utrecht/NL

Conclusion
We were able to establish a murine model for solitary liver metastases in which recurrent tumor arises after ILC treatment. Combination of interstitial laser coagulation and doxorubicin had a strong synergistic effect leading to complete tumor remission in all animals treated. These results provide a solid base for further investigation of combined treatment of chemotherapy and ILC for colorectal metastases.